Familial colorectal cancer risk in half siblings and siblings: nationwide cohort study
نویسندگان
چکیده
منابع مشابه
Cholesteatoma risk in 8,593 orofacial cleft cases and 6,989 siblings: A nationwide study.
OBJECTIVES/HYPOTHESIS To estimate the risk of surgically treated middle ear cholesteatoma in individuals with a nonsyndromic orofacial cleft and in their siblings compared with the general population. STUDY DESIGN Historical cohort study. METHODS Using the unique civil registration number for linkage, data from three national registers were used for the Danish 1936-2009 birth cohorts. Hazar...
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BACKGROUND AND METHODS Familial occurrence of immunoglobulin-related (AL) amyloidosis has occasionally been reported. In this work we describe the concomitance of systemic amyloidosis and monoclonal gammopathy (one case of Waldenström's macroglobulinemia and two cases without multiple myeloma or related diseases) in three Italian siblings, two males and one female. RESULTS AND CONCLUSIONS All...
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Primary familial hemophagocytic lymphohistiocytosis (HLH; or familial erythrophagocytic lymphohistiocytosis [FEL]) is a heterogeneous autosomal recessive disorder more prevalent with parental consanguinity. There is aggressive proliferation of activated macrophages and histiocytes, which phagocytose red blood cells (RBCs), white blood cells (WBCs), and platelets, leading to anemia, neutropenia ...
متن کاملShort Communication Familial Risks for Cervical Tumors in Full and Half Siblings: Etiologic Apportioning
Many studies have shown familial aggregation for cervical cancer, but they have been unable to distinguish between shared environmental and genetic effects. Full and halfsiblings were identified from the nationwide Swedish Family-Cancer Database, including invasive and in situ cervical cancers in women up to age 70 years. Half-siblings were defined through a common father or mother. Standardize...
متن کاملFamilial risks for cervical tumors in full and half siblings: etiologic apportioning.
Many studies have shown familial aggregation for cervical cancer, but they have been unable to distinguish between shared environmental and genetic effects. Full and half-siblings were identified from the nationwide Swedish Family-Cancer Database, including invasive and in situ cervical cancers in women up to age 70 years. Half-siblings were defined through a common father or mother. Standardiz...
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ژورنال
عنوان ژورنال: BMJ
سال: 2019
ISSN: 0959-8138,1756-1833
DOI: 10.1136/bmj.l803